Alternative pain treatment options are necessary to address the opioid crisis and the high prevalence of chronic pain. There is an increasing number of chronic pain patients not achieving their pain management goals, and there is a lack safe options to address chronic pain1.
Cannabis has better safety profile than opioids, with no reported deaths directly due to overdose. In the U.S, in the states with legalized cannabis, there was a reduction in opioid-related mortality and opioid prescriptions2.
Furthermore, our body’s own endocannabinoid system and opioid system interact synergistically with major pain pathways. Cannabinoids have several mechanisms of action to produce pain relief, whereby cannabinoid receptors are present in the peripheral and central nervous system, and in immune cells.